Sensory Maturation of Preterm Infants: From Visual Sensitivity to Multisensory Perception
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pediatrics
- Sponsor
- University Hospital, Strasbourg, France
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- visual stimulus detection with luminance
- Last Updated
- 8 years ago
Overview
Brief Summary
We aim to increase our knowledge of the impact of preterm birth on the maturation of the visual and auditory systems and on the development of multisensory perception
Specifically, we aim to evaluate the preterm infants' capabilities of detection and discrimination of different visual and auditory stimuli according to gestational age, post menstrual age and the duration of the postnatal life.
A secondary aim is to compare this competencies in preterm and full term control art term equivalent age.
The final aim is to optimize the hospital environment in order to make it correspond to the expectations and sensory abilities of very preterm infants.
Our hypothesis is that preterm birth exposes the infants to numerous atypical stimuli which could accelerate the processes of sensory maturation
Investigators
Eligibility Criteria
Inclusion Criteria
- •Newborn less than 32 weeks PMA hospitalized in the Hospital of Hautepierre, Strasbourg, France)
- •Consent obtained from both parents
- •Social insurance coverage
Exclusion Criteria
- •Any known malformation
- •Brain lesions discovered on brain ultrasound (Intra-Ventricular hemorrhage grade III or IV periventricular Leukomalacia).
- •Unstable clinical State
- •Retinopathy Of Prematurity stage\> 2 or in zone 1
- •Family history of abnormal color vision.
- •Abnormalities in auditory testing
- •Transfer to another hospital expected before 40 week PMA
Outcomes
Primary Outcomes
visual stimulus detection with luminance
Time Frame: 3 months
in "green" condition in hospital, luminance ( 100 and 300 lux ) and color (blue- red-yellow- white) variables
auditory stimulus detection with parents voice
Time Frame: 3 months
use parents voice, pure sound of 500 Hz
Secondary Outcomes
- behavioral responsiveness to visual stimuli calibrated collected from video recordings(3 months)