The effect of two different doses of Magnesium Sulfate on prevention of pain during Etomidate injectio

Phase 3

Conditions: Pain due to Etomidate injection.

Registration Number: IRCT20090129001615N6

Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 90

Inclusion Criteria

1. All patients who need to anesthesia With Etomidate Aged 18-65 years with ASA (American Society of Anesthesiologists) grade:1 or 2
2. No History of allergy to Magnesium
3. candidate for Elective Surgery

Exclusion Criteria

1. Patients with neuromuscular disease
2. Patients who have Difficulty Communicating
3. Myocardial Ischemia
4. Cardiac Arrhythmia
5. Seizure
6. Endocrine and Metabolic Diseases
7. Mental Disorders
8. Severe Neurological Disease
9. People without a vein in the back of the hand
10. Pregnancy
11. Liver and kidney diseases
12. Thrombophlebitis
13. Chronic pain
14. pancreatic disorders
15. Patients receiving sedative or analgesic drugs
16.Substance abusers

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity during Etomidate injection. Timepoint: Every minute until 10 minutes after Etomidate injecting. Method of measurement: Pain intensity is evaluated with using a 4-point Likert scale including: 0=no pain, 1=mild (pain expressed in response to the patient's question and without symptoms), 2=moderate (pain expressed in response to the patient's question) can be expressed along with the symptoms of the disease or pain spontaneously without asking the patient), 3=severe (a strong facial response or a response accompanied by arm withdrawal or facial grimacing) is measured.

Secondary Outcome Measures

Name	Time	Method
Blood pressure. Timepoint: Every minute after Etomidate injection up to 10 minutes. Method of measurement: Pulse oximeter.;Heart rate. Timepoint: Every minute after Etomidate injection up to 10 minutes. Method of measurement: Pulse oximeter.