Comparison of effect of intravenous 2 drugs (Magnesium sulphate and Dexmedetomidine) on intra-operative dose requirement of an anaesthetic agent (propofol), changes in vital parameters and recovery from anaesthesia in patients undergoing laparoscopic cholecystectomy
Not Applicable
- Registration Number
- CTRI/2021/09/036199
- Lead Sponsor
- Government medical College new civil hospital surat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
a)Patients belonging to ASA gradeI,II or III.
b)Patients between the age group of 18-60 years of either sex.
c)Patients posted for laparoscopic cholecystectomy surgeries under
general anaesthesia.
d)Patients giving valid informed written consent.
Exclusion Criteria
a)Patients with BMI >30kg/m2.
b)Patients with major hepatic,renal,cardio-respiratory disorder
and neuromuscular disorders
c)Patients with pregnancy,epilepsy,postural hypotension.
d)Patient who are taking CCBs,B-blockers,opioidsorsedatives.
e)Patients having allergy to studydrugs..
f)Known or suspected difficult airway.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare <br/ ><br>1) Intra-operative propofol requirements in mg/kg/hr <br/ ><br>2) Recovery Profile <br/ ><br>3) Post operative sedation with Ramsay sedation scoreTimepoint: From baseline to 12 hours <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare <br/ ><br> 1) Intra-operative haemodynamic changes. <br/ ><br> 2) Adverse effects if any.Timepoint: Minimum 3 hours