Comparison of the effect of intravenous magnesium sulfate and labetalol on intraoperative bleeding and postoperative edema and ecchymosis in rhinoplasty
Phase 3
Recruiting
- Conditions
- Condition 1: Bleeding during rhinoplasty. Condition 2: Edema and ecchymosis after rhinoplasty.
- Registration Number
- IRCT20211108053010N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
over 18 years old
consent to participate in the study
Exclusion Criteria
history of hypertension
peripheral vascular problems
renal, hepatic or hematologic disorders
pregnancy
obesity
diabetic neuropathy
uncontrollable hypertension
previous treatment with any antihypertensive drug, opioid or anticoagulant
magnesium supplementation
consumption Chronic drug
drug use such as aspirin
allergy to magnesium sulfate, drugs or other drugs under study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of bleeding during the operation. Timepoint: End of operation. Method of measurement: Measure lost blood by examining gases and suction.;The rate of ecchymosis. Timepoint: 24 hours and one week after surgery. Method of measurement: Standard tool for scoring degree of ecchymosis.;The amount of edema. Timepoint: 24 hours and one week after surgery. Method of measurement: Standard tool for scoring degree of edema.
- Secondary Outcome Measures
Name Time Method Sore throat. Timepoint: Postoperatively and 24 hours after surgery. Method of measurement: 4 degree scale of sore throat.;Headache. Timepoint: 24 hours after surgery. Method of measurement: Question.;Orthostatic hypotension. Timepoint: 24 hours after surgery. Method of measurement: Barometer.;Respiratory depression. Timepoint: 24 hours after surgery. Method of measurement: See the number of breaths per minute.;Surgeon consent. Timepoint: After surgery. Method of measurement: Boezaart criteria.