The effect of magnesium sulfate on hemodynamic complications of laparoscopy
- Conditions
- aparoscopic cholecystectomy.Calculus of gallbladder without cholecystitis
- Registration Number
- IRCT2013022311398N2
- Lead Sponsor
- Research Deputy of Medicine Faculty, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
consent to participate in research projects - patients scheduled for surgery of laparoscopic cholecystectomy with pneumoperitoneum gas CO2 - Age 70-20 years - physical patients with class ASA I-II .
Exclusion criteria: chronic use of drugs beta-adrenergic and calcium-channel blockers - drugs, psychotropic substances, use of lithium, other drugs such as hemodynamic TCA -
history of cardiovascular diseases - sensitivity to magnesium sulfate - diseases such as hypertension, diabetes mellitus, renal disease, acute cholecystitis and endocrine or metabolic disease.
Cases who develope complications also would be excluded. Also conversion of laparoscopic cholecystectomy to open surgery because of technical problems.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean arterial blood pressure. Timepoint: Before and after induction, before pneumoperitoneum, and every 10 minutes after pneumoperitoneum and after surgery. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.;Heart Rate. Timepoint: Before and after induction, before pneumoperitoneum, and every 10 minutes until 60 minutes after pneumoperitoneum and after surgery. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.
- Secondary Outcome Measures
Name Time Method Rate of usage of Propofol. Timepoint: One time at the end of surgery. Method of measurement: The mean dose per kilogram of body weight per minute.;Sedation quality of the patient in recovery. Timepoint: Every 15 minutes. Method of measurement: Clinical evaluation using Ramsay sedation score system.;Patient's pain acuty during recovery. Timepoint: Every 15 minutes. Method of measurement: According to VAS rating score.;TNG consumption rate. Timepoint: End of study. Method of measurement: Measuring amount of consumed drug.