IRCT20130518013359N5尚未招募3 期
The effect of Memantine on the severity of symptoms and brain function in patients with Obsessive-Compulsive Disorder (OCD) : An Event Related Potential (ERP) study
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •Patients with obsessive-compulsive disorder who have been treated with high doses of SSRI for at least 8 weeks but whose Y-BOCS index is higher than cut-off 15.
- •People aged 18 to 60 years
- •Obtain patient informed consent
排除标准
- •Pregnancy or breastfeeding
- •Using serotonergic drugs other than SSRIs
- •Use of NMDA receptor antagonists other than memantine
- •Psychotic and bipolar disorders (based on DSM-5 criteria)
- •Major Depressive Disorder (Based on DSM-IV-TR Criteria)
- •Other anxiety disorders (such as panic disorder, post-traumatic stress disorder (PTSD), general anxiety disorder (GAD)
- •Abuse or dependence on drugs or alcohol
- •Liver dysfunction (LFT> 3ULN)
- •Kidney dysfunction (GFR <60 ml / kg / min)
- •Thyroid Disorders (Based on Thyroid Function Test)
- •History of seizures
- •Cognitive-behavioral therapy
研究者
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