Clinical Trial to compare the effectiveness of Chlorhexidine at lower concentrations for Pneumonia development in ventilator assisted patients

Not Applicable

Completed

• Conditions: Health Condition 1: J13- Pneumonia due to Streptococcus pneumoniae

• Registration Number: CTRI/2019/05/019116
• Lead Sponsor: Dr Nagesh Vyas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-06-30
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 113

Inclusion Criteria

1. Male or female patients of age 18 to 75 yrs,

2. Requiring mechanical ventilation for at least more than 72 hours with normal hemodynamics with or without vasopressor

Exclusion Criteria

1. Known case pneumonia

2. Development of pneumonia within 48 hours of intubation

3. Chronic Obstructive Lung Disease with active chest infection; patients

4. Patients already received mechanical ventilation for more than 24 hours

5. Patients who have aspirated/with chest x-rays already showing infiltrates

6. Oral mucositis: It may cause local irritation and hypersensitivity.

7. Legal incarceration (e.g., organ transplantation or patients having long-term steroid therapy): They have a chance of hypersensitivity reaction.

8. Patients who died or were discharged within 48 hours of admission in the ICU.

9. Patients receiving immunosuppressive therapy or who were hypersensitive to chlorhexidine gluconate

Study & Design

• Study Type: Interventional
• Study Design: Not specified