Comparative effect of chlorhexidine mouthwash with plant-based mouthwash in the prevention of pneumonia

Phase 2

• Conditions: Ventilate-related pneumonia.; Ventilator associated pneumonia; J95.851

• Registration Number: IRCT20200413047059N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 November 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Age over 18 years
Requires mechanical ventilation for at least 48 hours
Do not use the chip pipe before entering the intensive care unit
No specific lesions in and around the mouth
Lack of safety defects
Do not take antibiotics before hospitalization
No pregnancy
Lack of allergy to plant compounds
Has natural teeth
Free and informed written consent of the patient's companion or guardian to participate in the study

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ventilator-related pneumonia. Timepoint: At the beginning of the study and 3 weeks after using two mouthwashes. Method of measurement: A microbial infection of the lung that occurs more than 48 hours after mechanical ventilation with a ventilator. Diagnosis of this type of pneumonia is based on the symptoms of pulmonary infection (including: purulent discharge, fever and leukocytosis), bacteriological evidence of pulmonary infection, and evidence of lung infection on specific radiographic images.