Randomized Control Trial on Short Term Effect of High versus Low Position of Umbilical Catheter in Neonates

Not Applicable

• Conditions: Aortic thrombosis; Peripheral vascular compromise; Intraventricular haemorrhage; Necrotising enterocolitis; Hypertension; Haematuria; Acute kidney injury; neonatal umbilical artery catheter; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system; Neurological - Other neurological disorders

• Registration Number: ACTRN12624000331538
• Lead Sponsor: Hospital Universiti Sains Malaysia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-03-25
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1) Patients who requiring umbilical artery catheter insertion
2) All term and preterm babies with gestational age equal to or more than 24 weeks
3) All term and preterm babies with weight more than 500g

Exclusion Criteria

1) Umbilical cord infection- Omphalitis
2) Newborn with major congenital abnormalities
3) Clinical evidence or suspected abdominal wall and viscera infection such as necrotizing enterocolitis or peritonitis.
4) Newborn with hematuria secondary to urinary tract infection
5) Breech presentation with lower limbs bruises

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
acute kidney injury[will be assess by monitor renal function test using blood sample and urine output frequency of assessment will be day 1 of umbilical artery catheter insertion, day 7 of life and day 14 of life.];aortic thrombosis [will be assessed using Doppler ultrasound frequency of assessment will be day 1 of umbilical artery catheter insertion, day 7 of life and day 14 of life.];intraventricular haemorrhage .[will be assessed using cranial ultrasound frequency of assessment will be day 1 of umbilical artery catheter insertion,day 7 of life and day 14 of life]

Secondary Outcome Measures

Name	Time	Method
Complications following UAC position readjusment- aortic thrombosis, acute kidney injury and intraventricular hemorrhage[ultrasound scan, x-ray frequency of assessment will be day 1 of umbilical artery catheter insertion, day 7 and day 14 of life];Rate of complications based on duration of UAC in-situ[ultrasound scan, x-ray frequency of assessment will be day 1 of umbilical artery catheter insertion, day 7 and day 14 of life]