Impact of tympanic membrane baroreceptors on Eustachian tube functio

Not Applicable

• Conditions: cholesteatoma, acute and chronical tube dysfunction; H71; Other specified disorders of Eustachian tube; H69.8; Cholesteatoma of middle ear

• Registration Number: DRKS00009327
• Lead Sponsor: Klinik und Poliklinik für HNO, Kopf- und HalschirurgieKlinikum der Universität zu Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

ear-healthy participants between the age of 18 and 70 years

Exclusion Criteria

- pregnancy,
- claustrophobia,
- exclusion if any operation was done on the ears,
- concurrent cold,
- inserted grommets or
- perforation of the tympanic membrane,
- adenoid hypertrophy,
- gastroesophageal reflux diseases, and
- signs and/or symptoms indicative of active allergic rhinitis.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ET opening pressure, ET opening duration, ET opening<br>frequency, and ET closing pressure will be determined before<br>and after local anaesthesia of the tympanic membrane

Secondary Outcome Measures

Name	Time	Method
- is a pressure equalization possible (yes/no)<br>- complete or incomplete openings of the eustachian tube during compression or decompression<br>- analysis of pressure progress