The Effect of Huel Powder on Appetite
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 主要终点
- Satisfied Visual Analogue Score
研究概览
简要总结
This project will assess the effect of Huel powdered food on the satiety of 40 generally healthy volunteers compared to a standard breakfast of cornflakes and milk.
To achieve this, we will recruit 40 (non-smoking) generally healthy volunteers to attend the study centre on two separate occasions. On each occasion they will arrive at the study centre fasted and will be given their breakfast of either Huel or Cornflakes and milk, matched for calorie content.
The aim is to identify the size and duration of any effect on satiety of the two meals.
详细描述
This project will assess the effect of Huel Food replacement on the satiety of 40 generally healthy volunteers compared to a standard breakfast of cornflakes and milk.
To achieve this, we will recruit 40 (non-smoking) generally healthy volunteers to attend the study centre on two separate occasions. On each occasion they will arrive at the study centre fasted and will be given their breakfast of either Huel or Cornflakes and milk, matched for calorie content.
We will ask volunteers to come to the research facility in Newcastle University, before they have had any breakfast, on two separate occasions. The volunteers must not eat or drink anything (except water) after 8 pm the evening before they come in. This includes not drinking any alcohol, tea, or coffee.
BMI, weight, and body composition (measured via electrical impedance) will also be taken at the initial visit to ensure they meet the inclusion criteria
All volunteers will be asked to complete screening questionnaires focusing on morning eating and exercise routine and the 'three factor eating' questionnaire before or during their screening visit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Generally Healthy
- •Non-pregnant/lactating
- •No known food allergies
- •BMI between 20-30
排除标准
- •Diagnosed eating disorder
- •receiving regular medication (except contraceptives or statins)
- •long-term illness such as high blood pressure, heart disease
- •taking medication that can affect kidney function
结局指标
主要结局
Satisfied Visual Analogue Score
时间窗: 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes
How satisfied do you feel?
How much can you eat Visual Analogue Score
时间窗: 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes
How much do you think you can eat?
Hunger Visual Analogue Score
时间窗: 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes
How hungry do you feel?
Fullness Visual Analogue Score
时间窗: 0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes
How full do you feel?
次要结局
- Insulin(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- PYY(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Ghrelin(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Fatty Visual Analogue Score(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- CCK(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Glucose(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Savoury Visual Analogue Score(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Sweet Visual Analogue Score(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)
- Salty Visual Analogue Score(0, 15, 30, 45, 60, 90, 120, 150, 180, 210, 240 minutes)