Palatability and Perceived Satiety of Oral Nutrition Supplements

Not Applicable

Completed

• Conditions: Sensory Evaluation; Perceived Satiety
• Interventions: Dietary Supplement: Oral Nutrition Supplement (ONS)

• Registration Number: NCT04397146
• Lead Sponsor: Wageningen University and Research

Brief Summary

The objective of the study is to evaluate palatability (primary objective) and perceived satiating effects (secondary objective) of two Oral Nutrition Supplements (ONS) prototypes and six commercially available ONS products. The products are matched on calorie content per portion.

The study is a single-blind intervention with a within-subjects design. In total 104 apparently healthy and independently living older adults aged 65 will be recruited to participate. Participants will visit the research facilities eight times in a period of one month. On each test-day participants will consume and evaluate a single product.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-02
• Primary Completion: 2019-10-31
• Study Completion: 2019-10-31
• Study First Submitted: 2020-01-07
• Status Verified: 2020-05
• Study First Submitted QC: 2020-05-19
• Last Update Submitted: 2020-05-19
• Study First Posted: 2020-05-21
• Last Update Posted: 2020-05-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 104

Inclusion Criteria

• Age 65 years or over
• Apparently healthy
• Living independently

Exclusion Criteria

• Allergies to soy, dairy or gluten
• Following a specific diet
• BMI>30 kg/m2
• Reduced kidney function
• Suffering from Alzheimer's disease, Dementia, Parkinson's Disease, Cancer, Kidney Disease or Diabetes
• Suffering from Dysphagia
• Already using oral nutritional supplements
• Receiving any medical treatment that is known to reduce the taste or sense of smell
• Current smokers
• Participation in another clinical trial at the same time

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Single-blind sensory and satiety evaluation	Oral Nutrition Supplement (ONS)	In total 8 different ONS products are consumed and evaluated, each product on a separate test day. The order of products is randomized between study participants.

Primary Outcome Measures

Name	Time	Method
Liking	Immediately after finishing consumption of a full portion of the ONS product	Questionnaire evaluating overall liking, liking of taste, liking of thickness and liking of aftertaste on a 11-points categorical scale ranging from 1='do not like at all' to 11='like very much'

Secondary Outcome Measures

Name	Time	Method
Satiety	2 hours after finishing consumption of a full portion of the ONS product	Feelings of satiety will be evaluated using a standardized questionnaire covering hunger (3 items), thirst (2 items) and fullness (1 item). Each item is answered on a 11-points categorical scale ranging from 1='not at all' to 11='very much'

Trial Locations

Locations (1)

Stichting Wageningen Research; 🇳🇱 Wageningen, Gelderland, Netherlands