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临床试验/NCT03134365
NCT03134365已完成不适用

Factors to Determine the Responses to Meal Ingestion: Palatability

Hospital Universitari Vall d'Hebron Research Institute2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2016年8月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
22
试验地点
2
主要终点
Meal palatability

研究概览

简要总结

Aim: to determine the effect of palatability on the cognitive (satiation/fullness) and emotive (digestive well-being/mood) responses to meal ingestion. The postprandial responses to conventional (potato and cheese cream followed by vanilla cream) versus unconventional test meals (mixture of both creams) with identical composition (350 Kcal) and physical characteristics (colour, texture, consistency, temperature) but distinctively different palatability will be studied on a cross over-design. The responses to the meals will be tested on 2 different days.

Participants (22 non-obese healthy men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 5 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • non obese

排除标准

  • history of gastrointestinal symptoms
  • prior obesity
  • use of medications
  • history of anosmia and ageusia
  • current dieting
  • alcohol abuse
  • psychological disorders
  • eating disorders

结局指标

主要结局

Meal palatability

时间窗: 1 day

Meal palatability measured by 10 score scales at the end of the test meal

Change in digestive well-being measured after the test meal

时间窗: 1 day

Change in average well-being measured by 10 score scales at the end of the test meal.

次要结局

  • Change in satiety measured after the test meal(1 day)
  • Change in mood measured after the test meal(1 day)
  • Change in fullness sensation measured after the test meal(1 day)
  • Change in abdominal discomfort/pain sensation measured after the test meal(1 day)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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