NCT02513758已完成不适用
Penetration and Compartimentation of HIV in Genital Mucosa
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Viral tropism of HIV
研究概览
简要总结
Genital mucosa is the main way of HIV penetration. Many cells can be involved (epithelial cells, Langerhans cells) and antibodies may also play a critical role. The investigators' study aims to precise the role of each type of cells, the interaction cell-cell and cell-antibodies.
详细描述
At inclusion, men will have a two blood sampling tubes of 10 ml each, a saliva sample and a sample of sperm and women will have a two blood sampling tubes of 10 ml each, a saliva sample and a sampling cervicovaginal secretions
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (> 18 year-old) HIV positive,
- •HIV-CV> 1000 cp/ml,
排除标准
- 未提供
结局指标
主要结局
Viral tropism of HIV
时间窗: Inclusion
number of HIV virus in sperm or cervical secretions.
次要结局
- Genetic polymorphism for HIV strains(Inclusion)
研究者
研究点 (1)
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