Flavonoids Kinetics Study
Completed
- Conditions
- Cardiovascular diseaseCirculatory System
- Registration Number
- ISRCTN36287115
- Lead Sponsor
- niversity of Reading (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
1. Healthy individuals
2. Male or female
3. Aged 20-50 years
Exclusion Criteria
1. Suffering from any form of known liver disease, diabetes mellitus or a myocardial infarction
2. Suffering from gall bladder problems or abnormalities of fat metabolism
3. On a weight reducing dietary regimen or taking any dietary supplements, including dietary fatty acids
4. Exercising more than three times a week for more than 20 minutes each session
5. Consuming more than 15 units of alcohol per week
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Vasodilation assessed using laser doppler imaging with iontophoresis<br>2. Vascular measurements were determined within 2 months of the end of the study
- Secondary Outcome Measures
Name Time Method The antioxidant status was measured by: <br>1. The ferric reducing antioxidant power (FRAP) assay<br>2. The oxygen radical absorbance capacity (ORAC) assay <br>3. By measuring the susceptibility of low density lipoprotein (LDL) to oxidation by a copper catalyst