Molecular Characterization of Perivascular Epithelioid Cell Tumors

Recruiting

• Conditions: Perivascular Epithelioid Cell Tumor, Malignant

• Registration Number: NCT05617105
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Perivascular epithelioid cell tumors (PEComas) are rare and are characterized by the expression of myomelanocytic markers. They are a complex family that includes angiomyolipomas, lymphangioleiomyomatoses and other soft tissue and visceral tumors. Due to the low prevalence of these tumors, the natural history is unclear; furthermore, a molecular classification integrating clinical, pathological and molecular parameters has not been described to date.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-01
• Status Verified: 2022-11
• Study First Submitted: 2022-11-07
• Study First Submitted QC: 2022-11-07
• Last Update Submitted: 2022-11-07
• Study First Posted: 2022-11-15
• Last Update Posted: 2022-11-15
• Primary Completion: 2022-12
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To retrospectively describe the percentage of tumors with FISH (Fluorescence In Situ Hybridization) identification of the TFE3 rearrangement out of 100 cases of PEComas diagnosed in France between 01 January 1990 and 15 September 2019	Files analysed retrospectively from January 01, 1990 to September 15, 2019 will be examined

Trial Locations

Locations (1)

Service d'Oncologie - CHU de Strasbourg - France; 🇫🇷 Strasbourg, France