The Horyzons trial: Moderated Online Social Therapy for Maintenance of Treatment Effects from Specialised First Episode Psychosis Services

Not Applicable

Completed

• Conditions: First episode psychosis; Mental Health - Schizophrenia; Mental Health - Psychosis and personality disorders

• Registration Number: ACTRN12614000009617
• Lead Sponsor: Orygen, The National Centre of Excellence in Youth Mental Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-03
• Study Completion: 2018-07-30
• Last Update Posted: 6 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 170

Inclusion Criteria

Inclusion criteria for the study will be:
(i) a first episode of a DSM-IV psychotic disorder or mood disorder with psychotic features
(ii) aged 16-27 years inclusive
(iii) less than or equal to 6 months treatment with an antipsychotic medication prior to registration with EPPIC
(iv) remission of positive symptoms of psychosis*
(v) less than or equal to 3 months to the due date of discharge from EPPIC
(vi) low aggressiveness**
(vii) moderate or lower suicidal risk***
(viii) able to nominate an emergency contact

*Remission of positive symptoms of psychosis is defined as 4 weeks or more of scores of 3 (mild) or below on the Positive and Negative Syndrome Scale (PANSS) items:
(i) conceptual disorganization (P2);
(ii) unusual thought content (G9);
score of 4 or below with no functional impairment on PANSS items:
(iii) hallucinatory behaviour (P3);
(iv) delusions (P1);

**Low aggressiveness is defined as a score of 3 or below on the poor impulse control item of the PANSS for the month prior to study entry

***Moderate or lower suicidal risk is defined as a score of 4 or below on the Brief Psychiatric Rating Scale - expanded version (BPRS) suicidality subscale for the month preceding study entry.

Exclusion Criteria

Exclusion criteria for the study will be:
(i) intellectual disability*
(ii) inability to converse in, or read English.
(iii)DSM-IV diagnosis of antisocial personality disorder (ASPD)
(iv) DSM-IV diagnosis of borderline personality disorder (BPD) with the additional criteria that the BPD features cause interpersonal difficulties in the treatment environment

Study & Design

• Study Type: Interventional
• Study Design: Not specified