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Clinical Trials/NCT02014090
NCT02014090
Completed
Not Applicable

Acute Cardiovascular Effects of External Counterpulsation (ECP) in Comparison With Physical Exercise in Healthy Individuals

Insel Gruppe AG, University Hospital Bern1 site in 1 country20 target enrollmentMarch 2008
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ConditionsPatients With Stable Coronary Artery Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Patients With Stable Coronary Artery Disease
Sponsor
Insel Gruppe AG, University Hospital Bern
Enrollment
20
Locations
1
Primary Endpoint
Myocardial Blood Flow (MBF) measurement by Myocardial Contrast Echocardiography (MCE)
Status
Completed
Last Updated
12 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study in humans with stable coronary artery disease (CAD) treatable by percutaneous intervention (PCI) is to evaluate the efficacy of Enhanced External Counterpulsation (EECP) with regard to coronary collateral growth.

Registry
clinicaltrials.gov
Start Date
March 2008
End Date
October 2011
Last Updated
12 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Christian Seiler

Prof Dr med

Insel Gruppe AG, University Hospital Bern

Eligibility Criteria

Inclusion Criteria

  • •Age \> 18 years, written informed consent to participate in the study

Exclusion Criteria

  • •Pregnancy (serum β-HCG\<2 IU/l for all female volunteers)
  • •Baseline History:
  • •Endurance exercise 5 days before and the days between the exams
  • •History of cardiovascular disease or surgery, including arterial hypertension, Raynaud phenomenon, recurrent migraine, or any cardiac rhythm disorder
  • •History of metabolic disorder, particularly diabetes mellitus
  • •History of respiratory, renal, hepatic or cerebral disease
  • •Allergic reactions to Luminity or its components
  • •Cardiovascular medication
  • •Illness characterized by acute phase response
  • •Anaemia with haemoglobin levels \< 110 g/L

Outcomes

Primary Outcomes

Myocardial Blood Flow (MBF) measurement by Myocardial Contrast Echocardiography (MCE)

Time Frame: During ECP respectively Bicycle Exercise, expected to be on average 90 minutes

Secondary Outcomes

  • Puls Wave Velocity Analysis(At baseline & post intervention, expected to be on average 90 minutes)

Study Sites (1)

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