Serological screening and metabolic analysis for evaluation of the immune response to SARS-CoV2 (COVID-19)
Recruiting
- Conditions
- COVID-19
- Registration Number
- DRKS00022292
- Lead Sponsor
- niversitätsklinikum Freiburg Klinik für Innere Medizin I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
Age at least 5 years, signed written informed consent form (for <18 years old, signed by the parent)
Exclusion Criteria
acute symptoms of COVID-19 in the last two weeks (fever, cough, shortness of breath)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is the level of IgM- and IgG antibodies against SARS-CoV2. The titers will be measured up to 3x within one year. In one part of the experiments we will also study the virus-specific Tcells.<br>
- Secondary Outcome Measures
Name Time Method The prevalence of antibodies in the population, a correlation between antibody titer, virus-specific T cells and symptoms; the correlation between metabolic parameters in immune cells, antibody titers and symptoms.