ISRCTN35917266已完成未知
The effect of Naltrexone, an Opiate Receptor Antagonist, on capsaicin dose-response in male Healthy volunteers (NORAH)
South Manchester University Hospital (UK)0 个研究点目标入组 20 人开始时间: 2012年9月10日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Male
入选标准
- •2. Aged 18 - 75 years old
- •3. Normal lung function
- •4. No current or past history of chronic cough or chronic respiratory illness
- •5. No current or past history of chronic pain, irritable bowel syndrome or chronic headaches
- •6. No current or past history of psychiatric illness
- •7. No current history of reflux disease or post-nasal drip syndrome
排除标准
- •1. Age >75 years
- •2. Recent upper respiratory tract infection (<4weeks)
- •3. Use of ACE inhibitors
- •4. Use of centrally acting medications that may affect the cough reflex
- •5. History of drug or alcohol abuse
- •6. Current smoker or ex-smoker with >10 pack year smoking history
- •7. A previous or current history of liver disease
- •8. Dependency on opioids
- •9. Current use of opiates
- •10. Known hypersensitivity to naltrexone
研究者
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