EUCTR2012-003409-86-BE进行中（未招募）1 期
The effect of naloxone and methylnaltrexone on oesophageal sensitivity in healthy volunteers: a randomized, double-blind placebo controlled study.
KULeuven0 个研究点目标入组 12 人开始时间: 2012年8月30日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1. Age >18 and <60 years
- •2. No history of GI disorders or symptoms
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 10
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. A history of allergic reaction to naloxon or methylnaltrexone or multiple allergies to several foods and drugs.
- •2. Pregnancy and/or lactation
- •3. Concomittant administration of monomine oxidase inhibitors, verapamil, or diltiazem or medications affecting oesophageal motility
- •4. Significant co-morbidities (neuro-muscular, psychiatric, cardiovascular, pulmonary, endocrine, auto-immune, renal and hepatic)
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