Acoustic Cardiographic Assessment of Heart Function and the Role of Phrenic Nerve Stimulation

Not Applicable

Completed

• Conditions: Heart Failure, Congestive; Transcutaneous Electric Nerve Stimulation; Cardiac Pacing, Artificial

• Registration Number: NCT00541541
• Lead Sponsor: Luzerner Kantonsspital

Brief Summary

In this study, the investigators sought to determine whether a stimulation of the phrenic nerve affects heart function. Heart function is assessed by acoustic cardiography.

Detailed Description

Patients who need temporary pacing following open heart surgery and who are willing to participate receive a phrenic nerve electrode during the operation. Heart function is postoperatively assessed by acoustic cardiography (Audicor, Inovise Medical Inc., Portland, USA) during different forms of pacing (right ventricle, left ventricle, biventricular; AAI, DDD) and with or without phrenic nerve stimulation. Acoustic cardiography simultaneously integrates heart sounds and single-channel electrocardiography input to generate multiple parameters that correlate to established hemodynamic measures. Effects of phrenic nerve stimulation on heart function will be analyzed.

Study Timeline

• Study Start: 2007-02
• Study First Submitted: 2007-10-08
• Study First Submitted QC: 2007-10-08
• Study First Posted: 2007-10-10
• Primary Completion: 2012-05
• Status Verified: 2013-04
• Last Update Submitted: 2013-04-16
• Last Update Posted: 2013-04-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients following open heart surgery who need temporary pacing

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Exclusion Criteria

• Patients with permanent pacemakers
• Patients with fast changing need of vasopressor therapy

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change of electrical mechanical activation time (EMAT) as measure of heart function on different settings of pacing	One day

Trial Locations

Locations (1)

Kantonsspital Luzern, Department of Cardiology; 🇨🇭 Luzern, Switzerland