Superficial and Deep Endometriosis: Role of Systemic Inflammation as a Marker of Clinical, Surgical, and Reproductive Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- Neutrophil to lymphocyte ratio
研究概览
简要总结
Primary aim of this study is to evaluate the change in systemic inflammation parameters after surgery for superficial, ovarian or deep endometriosis. Secondary objectives focus on correlating these parameters to clinical outcomes, in patients with pelvic pain, and reproductive outcomes, in women desiring offspring.
Participants already scheduled for surgery as part of their endometriosis care will be followed regarding the abovementioned outcomes after calculation of pre and postsurgical systemic inflammation markers (neutrophil to lymphocyte ratio; platelet to lymphocyte ratio and lymphocyte to monocyte ratio)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 45 years.
- •Postoperative follow-up of at least 12 months;
- •Signature of informed consent regarding laparoscopic surgical treatment.
- •Signature of informed consent to the processing of personal data duly documented by medical records.
排除标准
- •Failure to sign informed consent for laparoscopic surgical treatment
- •Histologic diagnosis of borderline tumor and/or ovarian carcinoma and/or mucinous cystadenoma and/or germ cell tumor or other malignancy of the genital tract
- •postoperative follow-up of less than 12 months;
- •documented history of inflammatory, rheumatologic, or immunologic disease; and
- •failure to provide informed consent for personal data processing.
结局指标
主要结局
Neutrophil to lymphocyte ratio
时间窗: Measured before and after (24 to 72 hours) surgery
次要结局
- Lymphocyte to monocyte ratio(Measured before and after (24 to 72 hours) surgery)
- Platelet to lymphocyte ratio(Measured before and after (24 to 72 hours) surgery)
研究者
Gaetano Riemma
MD
University of Campania "Luigi Vanvitelli"