MedPath

An Efficient Treatment for Posttraumatic Injury for Firefighters

Not Applicable
Recruiting
Conditions
Insomnia
Posttraumatic Stress Disorder
Nightmare
Interventions
Behavioral: Written Exposure Therapy (WET)
Behavioral: Waitlist
Behavioral: Cognitive Behavioral Therapy for Insomnia (CBTi)
Behavioral: Cognitive Behavioral Therapy for Nightmares (CBTn)
Registration Number
NCT05950035
Lead Sponsor
Palo Alto Veterans Institute for Research
Brief Summary

The goal of this two-arm pilot randomized controlled trial is to test a behavioral intervention that integrates three evidence-based cognitive behavioral interventions (written exposure therapy; WET, cognitive behavioral therapy for insomnia; CBT-I, and cognitive behavioral therapy for nightmares; CBT-N) among firefighters. The main questions it aims to answer are:

* Is the behavioral intervention feasible, acceptable, and effective in reducing symptoms of posttraumatic stress, insomnia, and nightmares?

* What is the efficacy of efficient treatment vs. delayed treatment (2-4 week waitlist) in reducing symptoms of posttraumatic stress, insomnia, and nightmares?

We will beta test the intervention in 1-2 groups of 3-5 firefighters. Then we will randomize 50 participants to immediate or delayed (2-4 week waitlist) treatment. Consented participants will:

* Complete self-report and interview measures assessing posttraumatic stress disorder, insomnia (PTSD), and nightmares

* Attend an individual treatment orientation session

* Attend a 4-day (\~3 hours per day over 4 consecutive days) group treatment that integrates WET, CBT-I, and CBT-N

* Attend an individual booster session held approximately one week later

* Complete self-report measures before, during, and after treatment, and at a 3-month follow up assessment and a clinical interview before and after treatment to assess program efficacy.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria
  • 18-65 years old
  • Firefighter
  • Able to speak and read English
  • Clinically significant posttraumatic stress symptoms: CAPS-5 total score ≥ 25; ≥ 1 intrusion symptom; ≥ 1 avoidance symptom
  • Clinically significant symptoms of insomnia: SCISD insomnia criteria are met; ISI ≥ 15
  • Clinically significant symptoms of nightmare disorder: SCISD nightmare disorder criteria are met, nightmares ≥ 1 monthly.
Exclusion Criteria
  • Current suicide or homicide risk meriting crisis intervention
  • Inability to speak and read English
  • Inability to comprehend the baseline screening questionnaires
  • Unwilling to remain abstinent from alcohol during treatment
  • Serious mental health diagnosis such as bipolar disorder or psychosis.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Immediate InterventionWritten Exposure Therapy (WET)Will begin treatment within 2 weeks of randomization.
Immediate InterventionCognitive Behavioral Therapy for Insomnia (CBTi)Will begin treatment within 2 weeks of randomization.
Delayed InterventionWaitlistWill be scheduled to begin treatment within 4-6 weeks of randomization.
Immediate InterventionCognitive Behavioral Therapy for Nightmares (CBTn)Will begin treatment within 2 weeks of randomization.
Primary Outcome Measures
NameTimeMethod
Structured Clinical Interview for DSM-5 Sleep Disorders- Revised (SCISD-R)Change from baseline to post treatment (~4 weeks post baseline)

The SCISD-R is a semi-structured interview designed to obtain a sleep history and screen for certain sleep disorders and diagnose others, including insomnia, hypersomnia, circadian rhythm sleep-wake disorders, sleep-disordered breathing, and parasomnias.

Insomnia Severity Index (ISI)Change from baseline through 3 months post treatment

The ISI assesses perceived severity of insomnia.

Nightmare Disorders IndexChange from baseline through 3 months post treatment

The NDI is a self-report assessment of nightmare disorder.

Clinician Administered PTSD Scale (CAPS-5)Change from baseline to post treatment (~4 weeks post baseline)

The CAPS-5 is a structured clinical interview that assesses the presence and severity of PTSD symptoms.

Posttraumatic Stress Disorder Checklist (PCL-5)Change from baseline through 3 months post treatment

Self-report measure update of the PCL designed to assess PTSD symptoms as defined by the DSM-5.

Secondary Outcome Measures
NameTimeMethod
Sleep Diary and Nightmare LogChange from baseline through post treatment (~4 weeks post baseline)

The Sleep Diary and Nightmare Log assess daily subjective sleep patterns and to inform treatment recommendations.

Trauma-Related Nightmare Survey (TRNS)Change from baseline through 3 months post treatment

The TRNS assesses nightmare frequency, disturbance, and characteristics.

Patient Health Questionnaire-9 (PHQ-9)Change from baseline through 3 months post treatment

The PHQ-9 the severity of affective and somatic symptoms related to depression; items correspond to the diagnostic criteria for major depression disorder.

Depressive Symptoms Index-Suicidality Subscale (DSI-SS)Change from baseline through 3 months post treatment

The DSI-SS is a self-report measure of suicidal ideation, plans, perceived control over ideation, and impulses for suicide.

Self-Assessment of Sleep (SASS)Change from baseline through 3 months post treatment

The SASS is a brief assessment of self-reported sleep quantity and sleep quality.

Net Prompter ScorePost treatment (~4 weeks post baseline)

The Net Prompter Score is a single item measures of treatment acceptability that asks respondents to rate the likelihood that they would recommend the efficient treatment to a friend or colleague on a scale from 0-10.

Trial Locations

Locations (1)

NDRI_USA

🇺🇸

Kansas City, Missouri, United States

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