A double-blind, placebo-controlled parallel-group pilot study of the effectiveness of D-cycloserine in reducing craving during cue-exposure therapy in abstinent alcohol-dependant subjects
Completed
- Conditions
- Mental and Behavioural Disorders: Alcohol dependenceMental and Behavioural DisordersAlcohol dependence
- Registration Number
- ISRCTN04481866
- Lead Sponsor
- Record Provided by the NHSTCT Register - 2006 Update - Department of Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 24
Inclusion Criteria
24 abstinent alcohol dependant males who attend the Bristol Area Specialist Alcohol Service. 12 in each group, D-cycloserine and placebo
Exclusion Criteria
1. Substance misuse or dependence (other than alcohol)
2. Major psychiatric morbidity such as psychosis
3. Clinically significant abnormality on physical examination or investigation
4. Pregnancy or breast feeding
5. Taking acamprosate, disulfiram or naltrexone
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method