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Brain Function and Decision-Making

Not Applicable
Completed
Conditions
Behavior, Social
Social Interaction
Interpersonal Relations
Psychology, Social
Interventions
Behavioral: Psychological task
Registration Number
NCT03974282
Lead Sponsor
Virginia Commonwealth University
Brief Summary

This study is about how brain function and structure is different between two universities. Participant in this project will contribute to a better understanding of how universities affect the brain.

Detailed Description

Some study details are purposely omitted at this time to preserve scientific integrity. Now that the study is completed, full details are included below.

The true purpose of this study was to investigate the psychometric properties of the two computer tasks that participants completed. Specifically, researchers wanted to know if they would be able to accurately measure motivated empathy. To better understand this, participants were asked to rate images of people expressing pain and were told that these were either students from their university or students from a different university. This was not the case. The faces shown were random images produced for a research study.

Researchers also wanted to know if they could accurately measure moral decision making and how those judgments relate to aggression. To examine this, participants were asked whether various scenarios were immoral and then asked about aggressive tendencies.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
36
Inclusion Criteria
  • Undergraduate students aged 18 - 35 years of age
  • No current or regular use of prescribed or illicit psychoactive drugs
  • Free of major health problems (e.g., diabetes, HIV, Parkinson's disease)
  • Free of a neurological or psychiatric disorders
  • No current drug abuse (e.g., recreational drug use, average alcohol intake in excess of 4 drinks per day).
  • Right hand dominant
  • Free of claustrophobia
  • Free of pregnancy or suspected pregnancy
  • Absent MRI risk factors (e.g., implanted medical device, body mass index > 35, braces)
  • Free of medical conditions that render individuals with overly sensitive hearing
  • No colorblindness
Exclusion Criteria

• Not meeting the inclusion criteria listed above.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
High psychopathy distributionPsychological taskParticipants who score at the high end of the psychopathy distribution
Low psychopathy distributionPsychological taskParticipants who score at the low end of the psychopathy distribution
Primary Outcome Measures
NameTimeMethod
Change in Accuracy of Empathic Pain JudgmentsBaseline to 3 hours

Difference in pain judgment scores rated from 1 (low) to 4 (high) between antisocial vs prosocial empathy trials

Change in Prefrontal Cortex Brain Activity Assessed by fMRIBaseline to 3 hours

Blood-Oxygen-Level-Dependent signal change in the cognitive empathy brain network will be assessed using functional MRI

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Virginia Commonwealth University

🇺🇸

Richmond, Virginia, United States

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