Multi-parametric Imaging in Personalized Radiotherapy
- Conditions
- Skull Base Chordoma
- Registration Number
- NCT05888064
- Lead Sponsor
- CNAO National Center of Oncological Hadrontherapy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria:<br><br> - Patients with histologically confirmed diagnosis of chordoma of the skull base<br><br> - Particle therapy with curative intent<br><br> - Karnofsky Performance status greater than or equal to 60<br><br> - Patients with macroscopic disease detectable at pre-radiotherapy imaging<br><br> - Patients undergoing PT with standardized treatment procedures<br><br> - Patients who have signed the written informed consent for research<br><br>Exclusion Criteria:<br><br> - Metastatic disease<br><br> - Palliative treatment<br><br> - Other malignancies with disease-free interval < 5 years (excepting pre- cancerous<br> lesions)<br><br> - Pregnancy<br><br> - Simultaneous CHT or Immunotherapy<br><br> - Extensive metal instrumentation/implants<br><br> - Patients with autoimmune diseases (ADs) -including collagen-vascular (CVD) and<br> inflammatory bowel (IBD)
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method collect data from MRI acquisition
- Secondary Outcome Measures
Name Time Method