Association between HDL functionality and coronary plaque in patients with stable angina and acute coronary syndrome
Not Applicable
Recruiting
- Conditions
- Coronary artery disease
- Registration Number
- JPRN-UMIN000012463
- Lead Sponsor
- Division of Cardiology, Fukuoka University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Not provided
Exclusion Criteria
1) hepatic failure 2) malignancy 3) active systemic inflammatory disease, before and after the operation, severe trauma 4) pregnant, lactating, or planned or possible pregnant 5) cardiogenic shock 6) ineligible for any other reasons
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Elucidate the association between HDL functionality and late loss, %Diameter stenosis, Minimum Lumen Diameter, Loss Index assessed with QCA. (Comparison among the groups and between baseline (0 month) and 6-12 month.)
- Secondary Outcome Measures
Name Time Method 1)Changes in characteristics of coronary plaque using IVUS (IB-IVUS, VH-IVUS). 2)Changes in characteristics of coronary plaque using OCT. 3)Association between serum lipids and coronary plaque. 4)Association between inflammatory markers and coronary plaque. 5)Difference of HDL functionality between healthy volunteer and CAD patients.