ISRCTN01688855
Completed
N/A
A magnetic resonance and histological investigation of articular cartilage damage in early stage degenerative disease of the hip joint and evaluation of synthetic labro-chondral graft implantation (INTCLAPH)
St George's University of London (UK)0 sites45 target enrollmentAugust 22, 2013
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Topic: Musculoskeletal
- Sponsor
- St George's University of London (UK)
- Enrollment
- 45
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. History of hip pain.
- •2\. Tönnis grade 0 or 1 radiographic changes.
- •3\. Hip Joint Space Width (JSW) \> 2 mm.
- •4\. Arthroscopic confirmation of:
- •4\.1\. Labro\-chondral split
- •4\.2\. Chondral defect grade 3 and 4 (Outerbridge, ICRS \& UCL Classifications)
- •4\.3\. Chondral defect size range 0\.5 ? 4\.0 cm2\.
- •5\. Ability to provide informed written consent.
- •Target Gender: Male \& Female; Upper Age Limit 55 years ; Lower Age Limit 18 years
Exclusion Criteria
- •1\. OA Grade \> 1 (Tönnis scale)
- •2\. Inflammatory joint disease
- •3\. Previous dislocation or fracture of the affected hip
- •4\. Previous non\-arthroscopic surgery to the affected hip
- •5\. History of back pain
- •6\. Age \<18 years and \> 55 years
- •7\. BMI \> 30
- •8\. Hip joint space \= 2 mm
- •9\. Previous hip joint sepsis or osteomyelitis
- •10\. Metabolic bone disease
Outcomes
Primary Outcomes
Not specified
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