The physiology of the anorectum, a pilot study
Completed
- Conditions
- ConstipationFecal obstruction10017977
- Registration Number
- NL-OMON45567
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
All subjects must be aged > 18 years.
Exclusion Criteria
A potential subject with self-report of bowel problems in a checklist, medical history of congenital abnormalities of the anorectal area, neurological dysfunction, current pregnancy and/or trauma or surgery on the gastrointestinal tract or pelvic floor with a possible influence on anorectal function, will be excluded from analysis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Because we hypothesize that the physiological regulatory mechanisms of<br /><br>anorectal function are located in the anal (sub)mucosa, we will compare all the<br /><br>physiological parameters obtained during anorectal function tests performed<br /><br>under two conditions: with an active superficial anal mucosa, and after its<br /><br>inactivation. In this way we will be able to indicate the regulatory factors,<br /><br>and also prove that that they are located in the anal mucosa or submucosa,<br /><br>which will be the outcome of this study. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable.</p><br>