Innovative Determination of Optimal Positive Expiratory Pressure to Increase Exercise Tolerance in COPD patients

Phase 2

Recruiting

• Conditions: Chronic Obstructive Pulmonary Disease; COPD; Exercise; Dyspnea; Dynamic hyperinflation

• Registration Number: TCTR20230124006
• Lead Sponsor: Khon Kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-24
• Study Completion: 2023-09-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

1. COPD patients GOLD stage II to IV.
2. Age between 40 to 80 years old.
3. Good communication, cooperation, and cognition.
4. Stable COPD (without acute exacerbation in the previous 4 weeks).

Exclusion Criteria

1. Medical diagnosis history of cardiovascular disease or related to the contraindication of exercise.
2. Home oxygen therapy (for at least 15 hours per day) or SpO2 < 88%.
4. Neuromuscular and musculoskeletal disorders.
5. Recent surgery.
6. Spontaneous bone fracture.
7. Acute lung embolism, lung infraction, or infection.
8. Severe arterial hypertension (Resting of systolic >200 mmHg or diastolic of >110 mmHg).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Exercise time End exercise time

Secondary Outcome Measures

Name	Time	Method
Dynamic hyperinflation End exercise Inspiratory capacity,Rate perceive of breathlessness Isotime Borg Dyspnea score