Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals
- Conditions
- Healthy Individuals (Controls)Chronic Cerebellar Stroke
- Interventions
- Device: Bimanual motor skill learning with the REAplan® rehabilitation robot
- Registration Number
- NCT04642599
- Lead Sponsor
- University Hospital of Mont-Godinne
- Brief Summary
To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).
- Detailed Description
Over 3 consecutive days, healthy individuals and chronic cerebellar stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan®.
They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks).
In addition, several "classical" clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...).
Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 50
- having a chronic cerebellar stroke (>6 months)
- aged 18-90 years
- with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
- difficulty in understanding or executing commands
- drug/alcohol abuse
- severe aphasia / cognitive deficits interfering with study
- inability to voluntarily move the affected arm (i.e. complete paralysis of the arm)
- multiple strokes / dementia / psychiatric condition
HEALTHY INDIVIDUALS:
Inclusion Criteria:
- 18-90 years
Exclusion Criteria:
- neurological conditions interfering with the study
- drug/alcohol abuse
- pyschiatric condition
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Chronic Cerebellar Stroke Bimanual motor skill learning with the REAplan® rehabilitation robot Participants with a chronic cerebellar stroke Healthy Individuals (Controls) Bimanual motor skill learning with the REAplan® rehabilitation robot healthy participants
- Primary Outcome Measures
Name Time Method Change in bi-CO Change between day 1 to 3 Bimanual Coordination factor measured by the REAplan robot bimanual Coordination factor : mathematical measure of the phase coherence between velocities of both arms
Change in bi-SAT Change between day 1 to 3 Bimanual Speed/Accuracy Trade-off measured by the REAplan robot bimanual Speed/Accuracy Trade-off: mathematical computation of the relationship bewteen speed and accuracy
- Secondary Outcome Measures
Name Time Method bi-error Day 1 + day 3 on bimanual REACHING (REAplan robot) Error in centimeters or degrees during bimanual reaching
Dextrain Day 1 + day 3 Kinetic device measuring the movements of each finger: force (Newton)
change in bi-Force Change between day 1 to 3 Bimanual forces : forces exerted in the wrong direction by each arm (Newtons)
bi-smoothness Day 1+ day 3 On bimanual REACHING (REAplan robot) Smoothness of movement : Spectral Arc Length (SPARC)
Corsi block Day 2 Tests the visuo-spatial memory
Montreal Cognitive Assessment (MoCA) Day 2 Tests the short-term memory, visuospatial skills, executive functions, attention, concentration, working memory, language and orientation in time and space
bi-Force Day 1 + day 3 On bimanual REACHING (REAplan robot)
bimanual forces : forces exerted in the wrong direction by each arm (Newtons)Abilhand and activlim Day 3 Questionnaire about the bimanual hability during activities of the daily life
bi-SAT Day 1 + day 3 On bimanual REACHING (REAplan robot) bimanual Speed/Accurady Trade-off: mathematical computation of the relationship
bi-CO Day 1 + day 3 On bimanual REACHING (REAplan robot) bimanual Coordination factor: mathematical measure of the phase coherence between velocities of both arms
BBT Day 1 + day 3 Box \& Blocks Test (timed transfert of blocks from one space to the other)
Modified International Cooperative Ataxia Rating Scale (MICARS) Day 1 Ataxia scale A high score describes strong ataxia and a low score describes weak ataxia
Fugl Meyer Upper extremity test Day 2 Tests impairments of the upper limb after stroke
Trial Locations
- Locations (1)
CHU UCL Namur, Mont-Godinne, Neurology Department, Stroke Unit
🇧🇪Yvoir, Namur, Belgium