Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Change in bi-CO
研究概览
简要总结
To test capacity of chronic cerebellar stroke patients and healthy individuals to learn and retain a complex bimanual motor skill, trained on the neurorehabilitation robot REAplan® (bimanual version).
详细描述
Over 3 consecutive days, healthy individuals and chronic cerebellar stroke patients (1) will be evaluated and (2) will train on the neurorehabilitation robot REAplan®.
They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks).
In addition, several "classical" clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...).
Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •having a chronic cerebellar stroke (>6 months)
- •aged 18-90 years
- •with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
排除标准
- •difficulty in understanding or executing commands
- •drug/alcohol abuse
- •severe aphasia / cognitive deficits interfering with study
- •inability to voluntarily move the affected arm (i.e. complete paralysis of the arm)
- •multiple strokes / dementia / psychiatric condition
- •HEALTHY INDIVIDUALS:
- •Inclusion Criteria:
- •18-90 years
- •Exclusion Criteria:
- •neurological conditions interfering with the study
- •drug/alcohol abuse
- •pyschiatric condition
结局指标
主要结局
Change in bi-CO
时间窗: Change between day 1 to 3
Bimanual Coordination factor measured by the REAplan robot bimanual Coordination factor : mathematical measure of the phase coherence between velocities of both arms
Change in bi-SAT
时间窗: Change between day 1 to 3
Bimanual Speed/Accuracy Trade-off measured by the REAplan robot bimanual Speed/Accuracy Trade-off: mathematical computation of the relationship bewteen speed and accuracy
次要结局
- bi-error(Day 1 + day 3)
- change in bi-Force(Change between day 1 to 3)
- bi-smoothness(Day 1+ day 3)
- Corsi block(Day 2)
- Montreal Cognitive Assessment (MoCA)(Day 2)
- bi-Force(Day 1 + day 3)
- Abilhand and activlim(Day 3)
- bi-SAT(Day 1 + day 3)
- bi-CO(Day 1 + day 3)
- BBT(Day 1 + day 3)
- Modified International Cooperative Ataxia Rating Scale (MICARS)(Day 1)
- Fugl Meyer Upper extremity test(Day 2)
- Dextrain(Day 1 + day 3)
研究者
Pr Yves Vandermeeren, MD, PhD
Professor
Université Catholique de Louvain