Radiofrequency Ablation of Genicular Nerves in Chronic Knee Osteoarthritis: A Randomized Controlled Trial of Local Anesthetic versus a combination of Local Anesthetic and Corticosteroid to alleviate post procedural neuritis

Not Applicable

• Conditions: Musculoskeletal Diseases; Post Radiofrequency Neuritis

• Registration Number: PACTR202204912139585
• Lead Sponsor: Ain Shams University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-16
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

•Age between 50 and 80 years.
•Presence of refractory knee pain of at least 3 months duration and at least grade 2 radiographic evidence of OA on the 5-point Kellgren–Lawrence scale.
•Numerical Rating Scale (NRS) score at Day 1 = 4 on chronic pain medication and = 6 if not on chronic pain medication.
•All patients should have a good response to the diagnostic genicular nerve block.

Exclusion Criteria

•Acute knee pain, prior knee surgery, other connective tissue diseases that affected the knee.
•Serious neurological or psychiatric disorders.
•Steroid, hyaluronic acid injection therapy or electroacupuncture treatment during the previous 12 weeks.
•Associated sciatic pain.
•Anticoagulant medication use.
•Pacemaker use.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduced or absent intensity of post radiofrequency neuritis with steroids

Secondary Outcome Measures

Name	Time	Method
Any complication related to RF ablation such as infection, haemorrhage, thermal injury, loss of motor, and or sensory control in the corresponding area of the involved nerves