Comparing Serum Interleukin 15 levels before and after radiofrequency ablation of genicular nerves in knee osteroarthritis patients.
- Conditions
- Health Condition 1: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2021/09/036718
- Lead Sponsor
- Department of Anaesthesiology ALL INDIA INSTITUTE OF MEDICAL SCIENCES RISHIKESH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients with symptomatic knee osteoarthritis (OA) that is recalcitrant to conservative modalities.
2.Patients with a failed knee replacement.
3.Patients who are not good surgical candidates because of medical comorbidities and/or a high body mass index (BMI).
4.Patients who want to avoid surgery.
5.Patients who have had a previously successful genicular nerve radiofrequency ablation (GNRFA), as this procedure can be repeated to address recurrent symptomatic knee OA.
1.Refusal of patient or relatives.
2.Allergic to local anaesthetic and/or radiographic contrast agent.
3.Coagulopathy or patients on anticoagulants.
4.Local site infection.
5.Pregnancy.
6.Severe psychiatric illness.
7.Red flag sign.
8.Acute knee injury.
9.Unstable knee joint.
10.Chronic pain syndrome.
11.Presence of an implantable defibrillator & Presence of a pacemaker.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of Serum interleukin 15 levels pre and post intervention.Timepoint: Baseline and 15 days post intervention
- Secondary Outcome Measures
Name Time Method Comparison of Numerical Rating scores (NRS) pre and post intervention.Timepoint: Baseline, 15 days, 1 month, 3 month post intervention;Comparison of WOMAC pain scores pre and post intervention.Timepoint: Baseline, 15 days, 1 month, 3 month post intervention