Pilot Study of the ANI (Analgesia Nociception Index) Validity on the Nociception Assessment in Healthy Volunteers in State of Hypnosis, Compared to Painful Numerical Verbal Scale (EVN).
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- University Hospital, Brest
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- EVN value of pain intensity versus average value of the ANI
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Healthy subjects should assess pain on a numerical scale (EN), during painful skin stimuli of variable intensity delivered by a CO2 laser used at the power of 0.3 W, known for its safety. ANI (Analgesia Nociception Index) will be raised simultaneously. This sequence will be made on subjects at rest and in a state of hypnosis using the technique of "remembering a pleasant memory" and the ideo-sensory technique of "protective glove".
The average value of the ANI will be compared to the value of the EVN of pain intensity.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Knowledge of the state of hypnosis
- •Healthy volunteers
- •Capable adults
- •Free and informed consent
Exclusion Criteria
- •Heart diseases
- •Medication affecting the heart rate
- •Medication affecting the skin sensitivity
Outcomes
Primary Outcomes
EVN value of pain intensity versus average value of the ANI
Time Frame: ANI average value : measured continuously for 60 seconds after the painful stimulation. EVN value : raised a few seconds after the painful stimulation
ANI value (0 to 100, without unit of measure) recorded continuously for 60 seconds after the painful stimulation compared to the EVN value of the pain intensity, from zero to ten (numerical verval scale), and this for each of 6 painful stimuli intensities of each three consecutive phases of the study.
Secondary Outcomes
- EVN value of the arduousness of pain perception versus ANI value(ANI average value : measured continuously for 60 seconds after the painful stimulation. EVN value : raised a few seconds after the painful stimulation)