Detection and analysis of HCV resistance to new HCV drugs and autologous antibody responses
Recruiting
- Conditions
- B18.2B17.1Chronic viral hepatitis CAcute hepatitis C
- Registration Number
- DRKS00010889
- Lead Sponsor
- niversität zu Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10000
Inclusion Criteria
confirmed replicative HCV-infection; intended start of renewed DAA-therapy; mental capacity; signed informed consent
Exclusion Criteria
age < 18 years
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identification of HCV resistant mutations before, during and after drug treatment using molecular biological methods like PCR
- Secondary Outcome Measures
Name Time Method up-grate public geno2pheno[hcv] server; correlation between cellular markers and treatment failures; identification of HCV-specific neutralizing antibodies<br>