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Clinical Trials/DRKS00012325
DRKS00012325
Recruiting
未知

Comparison of a conventional non-invasive ventilation to a non-invasive pursed-lip breathing ventilation (PLBV) ventilation in advanced COPD

Forschungszentrum Borstel0 sites256 target enrollmentAugust 14, 2017

Overview

Phase
未知
Intervention
Not specified
Conditions
COPD
Sponsor
Forschungszentrum Borstel
Enrollment
256
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 14, 2017
End Date
TBD
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Forschungszentrum Borstel

Eligibility Criteria

Inclusion Criteria

  • 1\. Age \>40 years
  • 2\. COPD diagnosis known for at least 12 months
  • 3\. NIV therapy for at least 3 months
  • 4\. Regular use of NIV with extrapolated usage time of at least 700 hours / year
  • 5\. Current inspiratory NIV pressure \=20 mbar
  • 6\. Patient understands the requirements of the study
  • 7\. Patient is able to follow the study protocol

Exclusion Criteria

  • 1\.Current COPD exacerbation (is allowed 4 weeks after end of treatment)
  • 2\.Radiologically proven pneumonia within the past month
  • 3\.Other leading pulmonary illness
  • 4\.Tracheostomy
  • 5\.Pneumothorax
  • 6\.Pregnancy or lactation
  • 7\.BMI \>35 kg/m²
  • 8\.Steroid therapy with \>15 mg prednisolon daily for \>1 month
  • 9\.Condition causing hypercapnia other than COPD
  • 10\.6MWT distance of \>300 meters within the last 7 days

Outcomes

Primary Outcomes

Not specified

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