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临床试验/NCT03965429
NCT03965429进行中(未招募)不适用

Immunological Follow-up After Allogeneic Hematopoietic Stem Cell Transplantation

Institut Paoli-Calmettes1 个研究点 分布在 1 个国家目标入组 1,020 人开始时间: 2019年5月14日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
1,020
试验地点
1
主要终点
Evolution of the immune blood populations in patients who have received allogeneic hematopoietic stem cell transplantation.

研究概览

简要总结

Description of the evolution of the biological characteristics of immune blood populations and biomarkers of interest in patients who have received allogeneic hematopoietic stem cell transplantation.

详细描述

a more in-depth analysis of the different immune cell sub-populations as well as serum markers (cytokines) would provide a better understanding of post-allograft immune reconstitution mechanisms and identify potential immunologic biomarkers predictive of GVH or relapse.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Allogeneic hematopoietic stem cell transplant for hematological malignancy
  • Patients 18 years of age or older
  • Signed consent to participation
  • Membership in a social security scheme, or beneficiary of such a scheme.

排除标准

  • A person of legal age subject to a legal protection measure (major under guardianship, curatorship or court bail), or unable to express consent (language criteria included).

结局指标

主要结局

Evolution of the immune blood populations in patients who have received allogeneic hematopoietic stem cell transplantation.

时间窗: 5 years after HSC transplantation

longitudinal study of the immune subpopulations of allografted patients for hematological malignancies.

次要结局

未报告次要终点

研究者

发起方
Institut Paoli-Calmettes
申办方类型
Other
责任方
Sponsor

研究点 (1)

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