Immunological Follow-up After Allogeneic Hematopoietic Stem Cell Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 1,020
- 试验地点
- 1
- 主要终点
- Evolution of the immune blood populations in patients who have received allogeneic hematopoietic stem cell transplantation.
研究概览
简要总结
Description of the evolution of the biological characteristics of immune blood populations and biomarkers of interest in patients who have received allogeneic hematopoietic stem cell transplantation.
详细描述
a more in-depth analysis of the different immune cell sub-populations as well as serum markers (cytokines) would provide a better understanding of post-allograft immune reconstitution mechanisms and identify potential immunologic biomarkers predictive of GVH or relapse.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Allogeneic hematopoietic stem cell transplant for hematological malignancy
- •Patients 18 years of age or older
- •Signed consent to participation
- •Membership in a social security scheme, or beneficiary of such a scheme.
排除标准
- •A person of legal age subject to a legal protection measure (major under guardianship, curatorship or court bail), or unable to express consent (language criteria included).
结局指标
主要结局
Evolution of the immune blood populations in patients who have received allogeneic hematopoietic stem cell transplantation.
时间窗: 5 years after HSC transplantation
longitudinal study of the immune subpopulations of allografted patients for hematological malignancies.
次要结局
未报告次要终点
