MedPath

THE MEDICAL COLLEGE OF WISCONSIN, INC.

🇺🇸United States
Ownership
-
Employees
-
Market Cap
-
Website

Clinical Trials

31

Active:4
Completed:15

Trial Phases

4 Phases

Phase 1:1
Phase 2:11
Phase 3:1
+1 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (16 trials with phase data)• Click on a phase to view related trials

Phase 2
11 (68.8%)
Not Applicable
3 (18.8%)
Phase 1
1 (6.3%)
Phase 3
1 (6.3%)

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Phase 2
Recruiting
Conditions
AML (Acute Myelogenous Leukemia)
Acute Lymphoid Leukemia (ALL)
Acute Leukemia (Category)
MDS (Myelodysplastic Syndrome)
CML (Chronic Myelogenous Leukemia)
CLL (Chronic Lymphocytic Leukemia)
Prolymphocyctic Leukemia
Chronic Myelomonocytic Leukemia (CMML)
Myeloproliferative Neoplasm (MPN)
Lymphoma
Interventions
Drug: Conditioning Regimen A
Drug: Conditioning Regimen B
Drug: Conditioning Regimen C
Drug: Conditioning Regimen D
Drug: Conditioning Regimen E
Procedure: Hematopoietic Cell Transplantation
Drug: PTCy (50 mg/kg D3, D4)
Drug: PTCy (25 mg/kg D3, D4)
Drug: Post-transplant Tacrolimus
Drug: Post-transplant Mycophenolate mofetil
Drug: Post-transplant Abatacept
Drug: Post-transplant Ruxolitinib
Other: Study treatment compliance
Other: Prohibited Concomitant Therapy
Other: Permitted Concomitant Therapy
First Posted Date
2025-03-05
Last Posted Date
2025-09-10
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
358
Registration Number
NCT06859424
Locations
🇺🇸

Stanford, Palo Alto, California, United States

🇺🇸

MD Anderson, Houston, Texas, United States

🇺🇸

University of Virginia, Charlottesville, Virginia, United States

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Chronic Myeloid Leukemia
Chronic Lymphocytic Leukemia
Chronic Myelomonocytic Leukemia
Acute Leukemia
Pro-Lymphocytic Leukemia
Acute Lymphoblastic Leukemia
Myelofibrosis
Myeloproliferative Neoplasm
Interventions
Procedure: PBSC Hematopoietic Stem Cell Transplantation (HSCT)
Other: Patient Reported Outcomes
Radiation: Total-body irradiation
First Posted Date
2023-08-21
Last Posted Date
2025-05-29
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
313
Registration Number
NCT06001385
Locations
🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇺🇸

Honor Health, Scottsdale, Arizona, United States

🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 29 locations

Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events

Active, not recruiting
Conditions
Acute Myeloid Leukemia in Remission
First Posted Date
2022-02-04
Last Posted Date
2025-04-25
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
303
Registration Number
NCT05224661
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

University of California, San Francisco, San Francisco, California, United States

🇺🇸

Stanford University, Stanford, California, United States

and more 15 locations

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

Recruiting
Conditions
Marrow Toxic Injury
Cellular Therapy
Allogeneic Stem Cell Transplantation
Autologous Stem Cell Transplantation
First Posted Date
2021-06-09
Last Posted Date
2023-05-03
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
99999999
Registration Number
NCT04920474
Locations
🇺🇸

NMDP Biorepository, New Brighton, Minnesota, United States

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Phase 2
Active, not recruiting
Conditions
Chronic Myelogenous Leukemia
Mixed Phenotype Acute Leukemia
Acute Leukemia
Acute Lymphoblastic Leukemia
Chronic Lymphocytic Leukemia
Acute Myelogenous Leukemia
Myelodysplastic Syndromes
Lymphoma
Interventions
Radiation: Total-body irradiation
Procedure: PBSC Hematopoietic Stem Cell Transplantation (HSCT)
Procedure: Bone Marrow Hematopoietic Stem Cell Transplantation
Other: Patient-Reported Outcomes
First Posted Date
2021-05-27
Last Posted Date
2025-07-29
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
300
Registration Number
NCT04904588
Locations
🇺🇸

City of Hope National Medical Center, Duarte, California, United States

🇺🇸

University of California San Francisco, San Francisco, California, United States

🇺🇸

Stanford University, Stanford, California, United States

and more 36 locations
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News

Real-World Data Confirms Low-Severity Safety Profile for Lisocabtagene Maraleucel Across Blood Cancer Settings

Real-world data from 877 patients and clinical trial data from 702 patients demonstrate that most cytokine release syndrome and neurological events with lisocabtagene maraleucel occur within 15 days of infusion and are not severe.

Real-World Data Shows Yescarta CAR-T Therapy Safe and Effective in Outpatient Setting

Kite presented real-world data from 238 patients showing comparable safety and effectiveness outcomes for Yescarta CAR-T therapy administered in outpatient versus inpatient settings for relapsed/refractory large B-cell lymphoma.

Experts Call for Ecosystem-Wide Approach to Address Disparities in Stem Cell Therapy Access

Leading experts at the 2025 Transplant and Cellular Therapy Meetings emphasize the critical need to address social vulnerabilities affecting patient access to stem cell transplants and CAR T-cell therapies.

ACCESS Trial Shows Promising Survival Rates with PTCy GVHD Prophylaxis in HLA-Mismatched Transplants

Phase 2 ACCESS trial demonstrates 84% one-year overall survival rate using post-transplant cyclophosphamide for GVHD prevention in HLA-mismatched unrelated donor transplants.

Dana-Farber Researchers to Present Groundbreaking Cellular Therapy Studies at 2025 Tandem Meetings

Dana-Farber researchers will showcase novel findings on multiple myeloma treatment outcomes based on Duffy genotype at the 2025 Tandem Meetings, revealing significant implications for personalized therapy selection.

Narsoplimab Shows Promising Real-World Outcomes in TA-TMA Patients at 2025 Tandem Meetings

Omeros Corporation will present real-world data from 128 transplant patients treated with narsoplimab for TA-TMA under an expanded access program at the 2025 Tandem Meetings in Honolulu.

Social Determinants Drive Disparities in Pediatric Stem Cell Transplant Outcomes and Access

Children from high-poverty neighborhoods face 25% transplant-related mortality compared to 20% in low-poverty areas, with Black children experiencing 65% higher risk of transplant-related mortality.

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