Cyclophosphamide

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

Cyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients.

• Acute Lymphoblastic Leukaemias (ALL)
• Acute Myeloid Leukemia
• Acute monocytic leukemia
• Adenocarcinoma of the Ovaries
• Breast Cancer
• Burkitt Lymphoma
• Chronic Lymphocytic Leukemia
• Chronic Myelogenous Leukemia (CML)
• Hodgkins Disease (HD)
• Lung Cancer
• Lupus
• Lymphocytic Lymphomas
• Lymphoma
• Multiple Myeloma (MM)
• Multiple Sclerosis
• Nephrotic syndrome with lesion of minimal change glomerulonephritis
• Non-Hodgkin's Lymphoma (NHL)
• Retinoblastoma
• Advanced Alibert-Bazin syndrome
• Chronic Granulocytic Leukemias
• Disseminated Neuroblastoma (NB)
• Histiocytic lymphoma
• Mixed-cell type lymphoma