Impact of Umbilical Cord Clamping Time on Infant Anemia

Not Applicable

Completed

• Conditions: Third Stage of Labor; Umbilical Cord Clamping Time; Infant Conditions; Healthy
• Interventions: Procedure: Delayed Clamping

• Registration Number: NCT04463485
• Lead Sponsor: Mersin University

Brief Summary

This research was conducted to carry out the effect of umbilical cord clamping time on baby anemia.

Detailed Description

This study is an experimental, randomized controlled study. The sample of the study consisted of 65 pregnant women and newborns (intervention=32, control=33) who applied for delivery at Ege University Medical Hospital Gynecology and Obstetrics Clinic at the time of the study. In this study, "Descriptive Data Form of Impact of Umbilical Cord Clamping Time on Infant Anemia" was used as a data collection tool. In the intervention group waited 60 seconds for umbilical cord clamping in the second stage of labor, in the control group the umbilical cord was clamped in the first 15 seconds. For the data of the first stage of the study, the neonatal hematocrit and bilirubin measurements and the need for phototherapy due to hyperbilirubinemia were evaluated 48 hours after birth. In the second stage of the study, data on anaemia screening performed in family medicine at the end of the fourth month of birth were examined. Statistical analysis of the data from the study was performed using IBM SPSS Statistics 25.0 package program. Parametric tests were used for statistical analysis of the data with a normal distribution. The level of statistical significance was determined as p\<0.05.

Study Timeline

• Study Start: 2017-12-21
• Primary Completion: 2018-08-30
• Study Completion: 2018-12-30
• Status Verified: 2020-07
• Study First Submitted: 2020-07-04
• Study First Submitted QC: 2020-07-04
• Last Update Submitted: 2020-07-08
• Study First Posted: 2020-07-09
• Last Update Posted: 2020-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• Apply for normal birth
• Singleton pregnancy and live fetus
• Cephalic presentation
• Estimated birth weight between 2500-4000 grams
• Birth rates <5
• Women who received iron support during pregnancy
• Haemoglobin level ≥ 11 gr/dL
• No systemic disease or pregnancy complication that may pose a risk for postpartum bleeding.
• Neonates who don't need for resuscitation after birth
• Babies who did not receive iron supplements up to the 4th month after birth were included.

Exclusion Criteria

• Pregnant women who refuse to participate in the research
• Neonates who need for resuscitation after birth
• Babies who receive iron supplements up to the 4th month after birth were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Delayed Clamping	Delayed Clamping	The intervention group was waited 60 seconds for umbilical cord clamping in the second stage of labor.

Primary Outcome Measures

Name	Time	Method
Haematocrit Values of 4 Month Infants	Infants' 4th month of age	Haematocrit measurement at baby's 4th month of age
Haemoglobin Values of 4 Month Infants	Infants' 4th month of age	Haemoglobin measurement at baby's 4th month of age
Diagnosis of Anemia Rates of 4 Month Infants	Infants' 4th month of age	Screening of the family medicine center, condition of the baby diagnosed with anemia at 4th month of age
Neonatal Bilirubin Value at 48th Hours of Life	48th hours after birth	Bilirubin measurement in capillary blood taken from newborn after birth
Neonatal Haematocrit Value at 48th Hours of Life	48th hours after birth	Haematocrit measurement in capillary blood taken from newborn after birth
Phototherapy Requirement Rates due to Hyperbilirubinemia	3 or 14 days of age	Neonatal phototherapy requirement due to hyperbilirubinemia in the postpartum period

Trial Locations

Locations (1)

Ege University Medical Hospital Obstetric and Gynecology Department; 🇹🇷 İzmir, Turkey