Comparing the impact of acute vigorous intensity or moderate intensity exercise with rest, on airway and systemic inflammation, oxidative stress and antioxidants in adults with asthma: a randomised controlled trial

Dr Hayley Scott0 sites56 target enrollmentMarch 27, 2015

Overview

No summary available.

Registry

who.int

Start Date

March 27, 2015

End Date

June 23, 2016

Last Updated

4 years ago

Study Type

Interventional

Sex

All

Sponsor

Dr Hayley Scott

•1\.Physician diagnosed asthma
•2\.Able to provide written informed consent
•3\.Females 18\-55 years of age or males 18\-45 years of age
•4\.Body mass index (BMI) \<\=40kg/m2
•5\.Not a current smoker (never smoker or quit at least 6 months ago)
•6\.Post\-bronchodilator forced expiratory volume in 1 second (FEV1\) \>\=50% predicted.
•7\.Approved for vigorous exercise by the study coordinator, according to the ESSA Adult Pre\-Exercise Screening Tool”.

•1\.Asthma is not the primary respiratory diagnosis
•2\.A moderate exacerbation (oral corticosteroid or antibiotic use) in the past four weeks or severe exacerbation (hospitalisation) in the past three months
•3\.Participation in a moderate\-vigorous intensity exercise session within 2 days of the scheduled study visit.
•4\.Known cardiac condition
•5\.Musculoskeletal contraindication to exercise
•6\.Uncontrolled hypertension (blood pressure \>180/100mmHg)
•8\.Diabetes mellitus
•9\.Thyroid disorder
•10\.Taking cholesterol lowering medication or ß\-blocker medication
•11\.Pregnancy or breastfeeding