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The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood

Not Applicable
Completed
Conditions
Healthy
Interventions
Dietary Supplement: Omega-3 fatty acids
Registration Number
NCT00615277
Lead Sponsor
University of Ulm
Brief Summary

The study investigates whether dietary intake of omega-3 long-chain polyunsaturated fatty acids affects learning and mood of healthy young adults.

Detailed Description

The long-chain polyunsaturated fatty acids (LCPUFA) EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) of the omega-3 series and AA (arachidonic acid) of the omega-6 series are building blocks of all cell membranes and are found in high concentrations in retina and brain. Food sources of LA and ALA are vegetable oils, nuts and seeds. Since low conversion rates from ALA to DHA are a characteristic of human metabolism, adequate dietary provision with the long-chained omega-3 molecules depends primarily on individual eating habits. While AA is abundant in meat and dairy products, EPA and DHA are found in noteworthy concentrations only in certain species of fatty fish, such as salmon or mackerel.

The study investigates whether participants receiving an omega-3 supplement over a period of 4 month, perform better on a series of cognitive tests, than the participants allocated to the placebo group.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
82
Inclusion Criteria
  • Healthy young adults
Exclusion Criteria
  • Coagulation disorder

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1Omega-3 fatty acids1: omega-3 fatty acid supplement
2Omega-3 fatty acids2: olive oil
Primary Outcome Measures
NameTimeMethod
CognitionBefore intervention and after 16 weeks of intervention
Secondary Outcome Measures
NameTimeMethod
MoodBefore intervention and after 16 weeks of intervention
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