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临床试验/NCT01925443
NCT01925443暂停不适用

Effects of Low Power Laser Therapy on Muscle Performance Isokinetic Pre-exercise in Individuals With Diabetes Mellitus Type II

University of Nove de Julho2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2015年12月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
暂停
入组人数
60
试验地点
2
主要终点
Muscle function

研究概览

简要总结

The low level laser therapy is able to improve immediately and long term (after 4 weeks of treatment, 3 days per week resulting in 12 applications of low level laser therapy) isokinetic muscle performance of the quadriceps femoris muscle (peak torque, total muscular work , maximum power and fatigue index - normalized by body weight) pre-exercise concentric isokinetic quadriceps femoris muscle in subjects with diabetes mellitus non-insulin-dependent.

详细描述

The low level laser therapy is able to improve after 4 weeks of treatment, 3 days per week resulting in 12 applications of low level laser therapy, the indicators: The low level laser therapy is able to improve immediately and long term (after 4 weeks of treatment, 3 days per week resulting in 12 applications of low level laser therapy), the indirect blood markers for muscle damage that evaluate the enzymatic activity of creatine Kinase (CK) and Lactate Dehydrogenase (LDH) and the visual analog scale (VAS-F) for fatigue, improves indicators F 2.2 point of the WHOQOL-100 for fatigue, improvement in functional indicators of the lower lower Extremity functional regarding Scale, functional improvement in performance in the execution of the test stand and sit and walk test six minutes, the indicators for quality improvement of life questionnaire for the Diabetes Quality of Life Measure and emotional states through the questionnaire Problems Areas in Diabetes Scale. Eligibility criteria: Diagnosis for Diabetes mellitus non-insulin-dependent confirmed by the individual physician, presenting between 30 to 70 years.Exclusion criteria: Diagnosis of cardiovascular disorders, diagnosis of diabetic neuropathy, which have a skin lesion or local infection (quadriceps), history of musculoskeletal injuries in the last 6 months or during the study, individuals unable to perform the assessment protocols / exercise so satisfactory, those who are doing some kind of regular physical activity and who underwent alcohol intake in the 24 hours before any of the stages of the study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
30 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis for Diabetes mellitus non-insulin-dependent
  • Age between 30 to 70 years

排除标准

  • Diagnosis of cardiovascular disorders
  • Diagnosis of diabetic neuropathy,
  • Skin lesion or local infection (quadriceps)
  • History of musculoskeletal injuries in the last 6 months or during the study
  • Individuals unable to perform the assessment protocols or exercise
  • Regular physical activity
  • Underwent alcohol intake in the 24 hours before any of the stages of the study

研究组 & 干预措施

Placebo group

Experimental

individuals will be subject to the application of low level laser therapy but with a dose of 0 Joules.

干预措施: Low level laser therapy (Other)

low level laser therapy

Experimental

individuals will be subject to the application of low level laser therapy, but this group will have three subdivisions related to dose in joules that will be administered to the individual, and J 4, J 6, 8 J. To be administered in the quadriceps muscle.

干预措施: Low level laser therapy (Other)

Control Group

No Intervention

will consist of individuals diagnosed with diabetes mellitus non-insulin-dependent, however, will not perform low level laser therapy, participate only in the evaluations

结局指标

主要结局

Muscle function

时间窗: 2 Years

Will use the isokinetic dynamometer to test and evaluate the human musculoskeletal system: peak torque and muscle fatigue of quadriceps.

次要结局

  • Muscle damage(2 year)
  • Muscle fatigue(2 years)
  • Quality of life(2 years)
  • Functionality(2 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Cid André Fidelis de Paula Gomes

Professor

University of Nove de Julho

研究点 (2)

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