Randomised Controlled Trial of Lanthanum carbonate vs Calcium carbonate on Vascular Calcification and Arterial Stiffness in Haemodialysis Patients: A Pilot Study

• Conditions: Cardiovascular disease and arterial stiffness in end-stage kidney disease; Renal and Urogenital - Kidney disease; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12607000046404
• Lead Sponsor: Department of Nephrology, Monash Medical Centre, Clayton

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-01-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients established on haemodialysis for at least 3 months.

Exclusion Criteria

If expected life-span <3 months; scheduled for renal transplant or parathyroidectomy in next 6 months; active peptic ulcer disease, and ulcerative colitis or Crohn's; and if on daily or nocturnal haemodialysis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in vascular calcification as measured by Computed tomography (CT) scans (of aorta and superficial artery) [At 12 months and 18 months]

Secondary Outcome Measures

Name	Time	Method
Changes in arterial stiffness (measured by pulse wave velocity) [at 3-6 month intervals];Changes in bone mineral density[at 18 months]