A randomized controlled trial of lanthanum carbonate versus calcium carbonate on coronary artery calcification in patients new to dialysis
Not Applicable
- Conditions
- End-stage renal disease (at the induction of dialysis)
- Registration Number
- JPRN-UMIN000006808
- Lead Sponsor
- Division of nephrology & kidney center, Kobe university graduate school of medicine.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients who have contraindication to lanthanum carbonate or calcium carbonate 2)Patients with history of parathyroidectomy 3)Gastrointestinal disorder 4)Patients with history of illeus 5)CAPD(continuous ambulatory peritoneal dialysis) 6)Pregnant and breast-feeding 7)Patients judged as being inappropriate for this study by investigators
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes of coronary artery calcification score (Agatston score)
- Secondary Outcome Measures
Name Time Method echocardiography, heart valve calcification, aortic calcification, vascular stiffness, carotid IMT, bone density, bone metabolic markers, ADMA, oxidative stress, high-sensitive CRP