Diaphragm Movement During Its Postural Function

Completed

• Conditions: Diaphragm Movement

• Registration Number: NCT04841109
• Lead Sponsor: University Hospital, Motol

Brief Summary

The aim of this study is to describe the movement of the diaphragm during postural activation of the trunk muscles in comparison with tidal breathing.

Detailed Description

Diaphragm movement will be measured by m-mode ultrasonography in a standing position. 30-35 healthy subjects will participate in the study. The movement of the diaphragm will be measured during tidal breathing then, during holding a load corresponding to 20% of the subject´s body weight and finally, during voluntary contraction of the trunk muscles. Trunk muscles contraction will be measured by a special device with pressure sensors placed on a trunk surface. Breathing activity will be measured by spirometry.

Study Timeline

• Study First Submitted: 2021-04-08
• Study First Submitted QC: 2021-04-08
• Study First Posted: 2021-04-12
• Study Start: 2021-05-22
• Status Verified: 2021-06
• Primary Completion: 2021-06-19
• Study Completion: 2021-06-19
• Last Update Submitted: 2021-06-28
• Last Update Posted: 2021-06-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• Signed informed consent form
• Able to comply with the study protocol, in the investigator's judgment
• Aged 20-40 years, inclusive
• Healthy as determined by the Investigator based on medical history, physical examination, vital signs and neurological examination
• Waist-to-height ratio < 0,59

Exclusion Criteria

• Low back pain (acute or chronic)
• Previous abdominal or spine surgery
• Acute or chronic respiratory or musculoskeletal disorder
• Any clinically significant illness, medical/surgical procedure or trauma within 4 weeks before initiation of the study
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diaphragm movement	6 months	Distance of the diaphragm from the ultrasound transducer in millimeters during tidal breathing, during holding a load, and during voluntary contraction of the trunk muscles

Secondary Outcome Measures

Name	Time	Method
Activity of the trunk muscles	6 months	Relative pressure in kilopascals generated by the trunk muscles during tidal breathing, during holding a load, and during voluntary contraction of these muscles
Tidal volume	6 months	Tidal volume in litres measured by spirometry during tidal breathing, during holding a load, and during voluntary contraction of the trunk muscles

Trial Locations

Locations (1)

Pavel Kolar´s Centre of Physical Medicine; 🇨🇿 Prague, Czechia