NL-OMON37491
Recruiting
Not Applicable
Hereditary breast cancer and the clinical significance of variants in the BRCA1 and BRCA2 genes. - Hereditary breast cancer and DNA Unclassified Variants.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- hereditary breast cancer
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 270
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) UV\-cohort: patients who are carrier of an unclassified variant.
- •2\) Affected relatives of the UV\-cohort patients will be invited for this study.
- •3\) At least one non\-affected family member of the UV\-cohort patients will be invited to take part in this study. ;The UV\-cohort consists of patients diagnosed with a primary breast tumor before the age of 60 years and are unrelated.
- •The patient can be included if only one unclassified variant is found in the BRCA1 or BRCA2 gene.
- •All the participants should be older than 18 years, competent and independent of the researcher.
- •They should all be informed about the study, its goal and its duration.
- •They know about the possibility of interim quitting the study.
Exclusion Criteria
- •\- Younger than 18 years old and older than 60 years old. Not affected family members may however, be older than 60 years old.
- •\-The participants should be competent to be able to make decision about participation.
Outcomes
Primary Outcomes
Not specified
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