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Study to compare the effect of benidipine and amlodipine on blood pressure and renal function in patients with type 2 diabetes mellitus and hypertension treated with angiotensin 2 receptor antagonists

Phase 4
Conditions
type 2 diabetes mellitus with hypertension
Registration Number
JPRN-UMIN000003315
Lead Sponsor
Kyoto University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients with cerebro-cardiovascular disease, such as unstable angina, acute myocardial infarction, and stroke within 6 months 2) Patients with congestive heart failure or severe arrhythmia 3) Patients with severe liver dysfunction 4) Patients with severe renal dysfunction or nephrotic syndrome 5) Pregnant patients 6) Patients allergic to benidipine or amlodipine

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
rinary albumin/creatinine ratio
Secondary Outcome Measures
NameTimeMethod
1) Blood pressure 2) urinary protein/creatinine, eGFR 3) safety
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