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A Retrospective Analysis of Raltegravir Use in Minority HIV Infected Women in Houston, Texas

Conditions
HIV Infection
Interventions
Registration Number
NCT02302950
Lead Sponsor
The University of Texas Health Science Center, Houston
Brief Summary

Raltegravir is the first marketed strand-transfer inhibitor of HIV-1 that was FDA approved in 2007. It is currently one of the preferred treatment regimens for HIV by the Department of Health and Human Services. It has become a widely used antiretroviral therapy option for HIV infected patients. It provides good tolerability and a favorable lipid profile for patients when compared to some other antiretroviral treatment options. Little data is reported about efficacy in a minority patient population. Moreover, data in an indigent minority population in the United States has not been aggregated before. Therefore this study will investigate the efficacy of raltegravir in minority women residing in Houston, TX who are HIV infected.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
254
Inclusion Criteria
  1. HIV-infected women who picked up raltegravir in the year 2013 at Thomas Street Health Center.
  2. Minority women -Black/African American, Hispanic/Latino
Exclusion Criteria
  • n/a

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
women that picked up raltegravir 2013raltegravirminority women that picked up raltegravir at Thomas street Health Center 2013
Primary Outcome Measures
NameTimeMethod
Assess the efficacy of raltegravir in study participants by measuring CD4 count and viral load24 weeks of therapy
Secondary Outcome Measures
NameTimeMethod
Capture data on concomitant conditions that may have led to participants switching to raltegravir from medical records (eg. Diabetes mellitus)24 weeks of therapy
Assess tolerability of raltegravir by capturing symptoms24 weeks of therapy

Trial Locations

Locations (1)

Thomas Street Clinic

🇺🇸

Houston, Texas, United States

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